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Why exosome therapy is 2025’s ‘It’ skincare trend

Every year, the world of skincare introduces a popular buzzword that sweeps the globe and even becomes part of our everyday language (collagen, we're looking at you!). Make a note of this one, because exosomes have captured our attention this year. Heralded as the 'new favorite' for supporting healthy skin and hair, exosomes have quietly become a hot topic. Millennials... does that ring a bell? It has now become a star in the spotlight, emerging as one of the most anticipated skincare trends for 2025. Let's explore why exosomes are creating such a stir!

But first...What Are Exosomes?

"Exosomes are tiny extracellular vesicles released by cells, containing proteins, lipids, and genetic material," explains Dr. Madhuri Agarwal, MD and founder of Yavana Aesthetics. Exosomes can communicate with adjacent or distant cells and carry and deliver effective molecules. This is one of the reasons they've become so popular.

These exosomes originate from various sources, such as mesenchymal stem cells and human umbilical vein endothelial cells. Dr. Jaishree Sharad, a cosmetic dermatologist and founder of Skinfinitii Aesthetic Skin and Laser Clinic, states, "Almost all types of normal cells can produce exosomes. They can be found in various cells, including human umbilical vein endothelial cells, mesenchymal stem cells (MSC), T cells, B cells, macrophages, dendritic cells (DC), and natural killer (NK) cells." In the beauty industry, exosomes used are often derived from mesenchymal stem cells, plant-based sources, or synthetic origins, all sharing the common goal of supporting skin cells.

Benefits of Exosomes in Skincare
Dr. Sharad states, "Exosomes can help improve skin tone, texture, and appearance, offering multiple potential age-defying benefits." They help maintain skin elasticity and plumpness, and enhance skin hydration, leaving skin softer and more radiant. Exosomal proteins and lipids can plump and moisturize the skin. They also brighten skin tone by helping to reduce the appearance of dark spots. Ingredients like cytokines, nucleic acids, and proteins can also protect the skin from environmental stressors, further reducing visible discoloration. This makes them a valuable tool for revitalized, radiant skin.

In-Clinic Vs Topical Care

Dr. Agarwal emphasizes that the stability of exosomes is crucial for product effectiveness. She further describes the process, stating that exosomes are applied to the skin. Due to their small size, they can easily penetrate microchannels, providing nourishment and conditioning at a deeper level. "Skin treatments are typically performed every three to four weeks, and hair treatments every 15 days."

Who Are Exosomes Suitable For?

Exosomes are recommended for individuals in their late 20s to 30s, a period when the natural resilience and restorative factors of the skin may begin to slow down. This is also when the effects of environmental aggressors become more apparent on the skin. They are suitable for those looking to smooth skin appearance, address concerns like fine lines, and improve overall skin texture.

Important Considerations from Experts
Experts note that while exosome applications, both professional and topical, are generally well-tolerated across all skin types, it's always wise to consult a dermatologist before incorporating any new advanced skincare into your routine. This ensures you receive personalized guidance for your skin's needs. While rare, potential sensitivities could include allergic reactions or irritation.

[Sparkling Sciences] Translated & Edited 
Source: Why exosome therapy is 2025's ‘It’ skincare trend - Harpers Bazaar